Medical Imaging Research Group (MIRG)

Doyley/Dartmouth Collaborative Paper Published

Congratulations to Marvin Doyley and his collaborators on the publication of their manuscript titled "Separation of solid stress from interstitial fluid pressure in pancreas cancer correlates with collagen area fraction."  The article appears in the Journal of Biomechanical Imaging: http://biomechanical.asmedigitalcollection.asme.org/article.aspx?articleid=2618331&resultClick=1.  Co-authors include Brian Pogue, Michael Nieskoski, Kayla Marra, Jason Gunn, Stephen Kanick, B. Stuart Trembly (Thayer School of Engineering, Dartmouth College), Tayyaba Hasan (Wellman Center for Photomedicine at Massachusetts General Hospital/Harvard Medical School), and Stephen Pereira (Institute for Liver and Digestive Health, University College, London).  The study described in this paper demonstrates "a new approach to measure interstitial fluid pressure and solid stress...with a modified pressure transducer.  These data grant insight into the mechanisms of collagen interaction with pressure and vascular patency within pancreatic tumors.