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"Volumetric tri-modal imaging with combined photoacoustic, ultrasound, and shear wave elastography"

July 21, 2022

Congratulations to Professor Doyley and PhD candidate Wentao on the publication of the journal article titled "Volumetric tri-modal imaging with combined photoacoustic, ultrasound, and shear wave elastography." University at Buffalo co-authors include Dr. Jun Xia, Emily Zheng, and Huijuan Zhang. This article appears in in the Journal of Applied Physics and describes collaborative research funded by the National Institutes of Health (grant number R01EB029596). The abstract appears below and more information can be found here.

Abstract: Photoacoustic imaging is a hybrid imaging approach that combines the advantages of optical and ultrasonic imaging in one modality. However, for comprehensive tissue characterization, optical contrast alone is not always sufficient. In this study, we combined photoacoustic imaging with high-resolution ultrasound and shear wave elastography. The multi-modal system can calculate optical absorption, acoustic reflection, and stiffness volumetrically. We constructed a multi-modal phantom with contrast for each imaging modality to test the system’s performance. Experimental results indicate that the system successfully visualizes the embedded structures. We envision that the system will lead to more comprehensive tissue characterization for cancer screening and diagnosis.