Danielle Benoit, Ph.D., assistant professor of Biomedical Engineering, has been awarded a two year grant from New York Stem Cell Science (NYSTEM), for the project, entitled: Promoting MSC-mediated musculoskeletal tissue regeneration using sustained, localized sirna delivery.This research will develop hydrogel-based, sustained and localized delivery systems for small interfering RNA (siRNA) to promote mesenchymal stem cell (MSC)-mediated tissue regeneration. Our initial application for this approach is as a delivery system to enhance fracture healing.