Researchers Find Intriguing New Tool for Tendon Healing: Nanoparticles for Precision Drug Delivery

June 20, 2024

alayna_loiselle

“There are very few effective drug regimens to assist the tendon healing process, despite the high number of these injuries and the poor outcomes that often result,” said Alayna Loiselle, PhD, associate professor at the University of Rochester’s Center for Musculoskeletal Research. “Systemic drug treatments delivered orally or via injection show poor tendon homing; in some cases, less than 1 percent of a systemically delivered medication reaches the healing tendon. Local administration of drugs directly to the tendon has disadvantages as well, including potential tissue damage from the injection and poor control over drug concentrations at the point of injury.”  
“We want to pivot from using suturing alone to incorporating therapeutics,” said Emmanuela Adjei-Sowah, a Biomedical Engineering PhD student at the University of Rochester...

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Allison Lopatkin named 2024 Pew Scholar in Biomedical Sciences

June 18, 2024

Allison Lopatkin ’13

Allison Lopatkin ’13, an assistant professor of chemical engineering, biomedical engineering, and microbiology and immunology at the University of Rochester, is one of 22 scientists selected to join the Pew Scholars Program in the Biomedical Sciences this year. The program provides early-career scientists four years of funding to explore some of the most pressing questions in human health and medicine.

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Upstate New York's Inaugural MPS Symposium Celebrates Success

June 7, 2024

unympss

On June 3, 2024, the inaugural Upstate New York MPS Symposium (UNY-MPSS 2024) was held at the University of Rochester. The event was a tremendous success, with nearly 100 attendees from over a dozen institutions from across Northeast America, including some representation from as far as the West Coast.

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BME Students Invent Tick Collection System For Researchers in Costa Rica

May 3, 2024

a mobilized tick collection system

Days before they are set to present their final design to the University of Rochester community during Design Day, a team of senior biomedical engineering students (Sarah Manning, Rachelle Gomez-Guevara, Lawrence Chen and Anjali Patel) tinkers with a small radio-controlled car they have tricked out to handle rough terrain, travel long distances, and carry flannel flags. For their senior design project, the team is creating a mobilized system to collect ticks in Costa Rica for further study by epidemiologists.

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Hearing, Balance & the Brain

April 25, 2024

Cover of "NeURoscience | Vol 21 | 2024"  NeURoscience | Vol 21 | 2024

Researchers at the University of Rochester and Medical Center (URMC) have long been on the quest to understand this system and its parts. Faculty from an array of disciplines, such as Neuroscience, Otolaryngology, Biomedical Engineering, Linguistics, and Brain and Cognitive Sciences, all aim to discover better drug-delivery methods and improve mechanistic and functional understandings of the hearing, balance, and brain connection. The University of Rochester is among the top 20 institutions in the United States in funding for hearing—and balance—related research from the National Institute on Deafness and Communication Disorders (NIDCD). It is one of the few institutions on that list that does not have a designated center for the group.  
     “Collaboration has been really key,” said Laurel Carney, PhD, professor of Biomedical Engineering and Neuroscience. “There are no barriers between different groups to get funding that crosses departmental or school boundaries. That is important.”

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Tochukwu Iyke-Nzeocha Earns Sue S. Stewart Award

April 15, 2024

Congratulations to biomedical engineering student Tochukwu Iyke-Nzeocha ’24 for earning the Sue S. Stewart Leadership and Community Service Award. Tochukwu was presented the award at the 2024 Susan B. Anthony Legacy Awards Ceremony on Saturday, 4/13. The annual award recognizes a senior woman undergraduate student whose life in the University has been distinguished by a commitment to justice, equality, and community service, as these relate to diversity and inclusion, particularly in the lives of girls and women; and whose activities reflect the spirit of these principles and dedication to these qualities as expressed and inspired by the life and career of former Senior Vice President and General Counsel of the University of Rochester, Sue Stewart. 

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Ernestina Domey Awarded Two Optica Scholarships

April 12, 2024

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Ernestina Domey, a first-year BME masters student working in the Baran Lab, has achieved an impressive milestone by receiving two prestigious Optica scholarships! Earlier this year, she was one of 10 students to be awarded the Optica Amplify Scholarship. More recently she was also selected as one of 20 Optica Women Scholars. These nominations were based on the innovative nature and potential impact of her research in the field of biomedical engineering and optical sciences.

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Tochukwu Iyke-Nzeocha Receives NSBE 2024 Edward E. Barnette Jr. Community Impact Scholarship

April 8, 2024

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Rochester’s chapter of the National Society of Black Engineers (NSBE) were among the 18,000 attendees at the NSBE 50th Annual Convention in Atlanta, Georgia this past March.  At the convention's NSBE Annual Golden TORCH Awards, Tochukwu Iyke-Nzeocha '24, BME major and president of the UR NSBE chapter, received the prestigious 2024 Edward E. Barnette Jr. Community Impact Scholarship. This scholarship recognizes individuals who demonstrate exceptional commitment to the NSBE mission and show promise in making a positive impact on their communities and society.

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Chloe Zhang Wins Award at AS&E Graduate Research Symposium

April 1, 2024

Chloe Zhang

Congratulations to Chloe Zhang, PhD candidate in Biomedical Engineering, for winning "best presentation" at the AS&E Graduate Research SymposiumZhang's poster, titled "Towards quantifying cerebral blood flow of patients undergoing extracorporeal membrane oxygenation (ECMO) with diffuse correlation spectroscopy (DCS) and speckle contrast optical spectroscopy (SCOS)", was recognized alongside two other engineering student posters in this year's "engineering and math" category.

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The Science Behind Solar Eclipse Glasses

March 21, 2024

UR Solar Eclipse Glasses

Properly protecting your eyes during a solar eclipse is crucial for avoiding long-term damage to your vision. In anticipation of the total solar eclipse happening in Rochester, New York, on April 8, 2024, James Zavislan, a professor of optics and of biomedical engineering and an associate professor of ophthalmology at the University of Rochester, wants everyone to understand the risks involved and how to have a safe, enjoyable eclipse experience.

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Improved Neuromonitoring Could Prevent Brain Injuries for Patients on ECMO Life Support

March 14, 2024

CEREBRAL TECHNIQUES
CEREBRAL TECHNIQUES: In a cardiac intensive care unit, Associate Professor Regine Choe (center) applies diffuse correlation spectroscopy (DCS) sensors to the head of Assistant Professor Imad Khan (right) while biomedical engineering PhD student Irfaan Dar (left) examines data.

Regine Choe, an associate professor of biomedical engineering and of electrical and computer engineering, and Imad Khan, an assistant professor of neurology and neurosurgery, have linked together multiple devices to evaluate different aspects of the brain’s health. The devices monitor the cortex, the brain’s outermost layer where neurons reside, using electroencephalography (EEG) to study electrical activity and a new optical method called diffuse correlation spectroscopy (DCS), which measures brain-blood flow. They also use evoked potentials—measurements of the electrical signals produced by the nervous system in response to an external stimulus— to examine deeper structures in the brain.

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Building Better Tools to Predict Kidney Injury in Kids

March 5, 2024

Dziorny

Children who come into the ICU for any number of reasons may wind up with acute kidney injury, a dangerous condition in which kidneys can no longer filter waste from the blood. If doctors catch the warning signs early, there are several things they can do to prevent acute kidney injury in kids, but it can be difficult to predict which patients are at risk.

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Printing Plant-based Pharmaceuticals—Without Plants

February 13, 2024

Ines Drissi Qeytoni in Lab
THE HEAT IS ON: iGEM team member Ines Drissi Qeytoni ’26 sterilizes an inoculation loop under flame while preparing bacteria overnight cultures in Hutchison Hall. (University of Rochester photo / J. Adam Fenster)

A multidisciplinary team of 10 undergraduates (including biomedical engineering majors: Ines Drissi Qeytoni, Allie Tay, and Wenqi Di) pioneered new technologies to more efficiently replicate useful chemicals found in plants, including those endangered by Earth’s changing climate. Calling themselves “Team RoSynth,” the students created an affordable 3D-printing system for optimizing production of in-demand, plant-derived drugs and pharmaceuticals.  In November, the team entered their research in the 2023 International Genetically Engineered Machine (iGEM) competition, an event in which student-led teams from around the globe compete to solve real-world problems using synthetic biology. Synthetic biology takes advantage of engineering to build biological parts inspired by nature. The Rochester team’s project was nominated for the Best Biomanufacturing Project and Best Hardware and was awarded a gold medal, making them the third most recognized team in the United States. The team competed against 402 teams from six continents.

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Alayna Loiselle Receives Orthopaedic Research Society’s Boskey Award

February 3, 2024

ORS - Adele L. Boskey Award: Alayna Loiselle

Congratulations to Dr. Alayna Loiselle on receiving the Orthopaedic Research Society’s Adele L. Boskey, PhD Award for her contributions to musculoskeletal research and mentorship of next-generation scientists. She leads the Loiselle Lab in the Center for Musculoskeletal Research, where her team’s work focuses on defining the fundamental cellular and molecular mediators of tendon homeostasis, tendinopathy development, and the tendon response to injury.  Dr. Loiselle is an associate professor in the Department of Orthopaedics, with joint appointments in Biomedical Engineering, and the Pathology & Laboratory departments. She was recognized for this award at the 2024 ORS Annual Meeting on February 4.

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BME Welcomes Dr. Cherice Hill

January 30, 2024

hill_cherice350x500.jpgWe are pleased to announce that as of January 2024, Dr. Cherice Hill has officially joined the faculty of the Department of Biomedical Engineering at the University of Rochester. Dr. Hill received a BS in Biomedical Engineering from the University of Virginia, and her MS and PhD in Biomedical Engineering from Virginia Tech, focusing on movement mechanics in diverse populations as they relate to injury and disease risk. She extended her training with a postdoctoral fellowship in the multidisciplinary Clemson-MUSC Bioengineering Program studying temporomandibular joint function, structural and mechanical influences of ligamentous structures, and related health disparities.

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New NIH-funded Center Could Soon Reduce the Need for Pharmaceutical Trials on Animals

January 9, 2024

bme poster session
TRaCE-bMPS PIs, Jim McGrath, Joan Adamo, Hani Awad and Ben Miller along with their teams, Kevin Webb (University of Nottingham), Leanna Levine (ALine Inc.) and James Roussie (SiMPore Inc.) Not shown, but part of the TRaCE-bMPS are PI George Truskey (Duke) and Co-I’s Niccolo Terrando (Duke), Harris Gelbard, Steven Gill, and Paul Dunman (UR), and Vinay Abhyakar and Thomas Gaborski (RIT). (University of Rochester photo / J. Adam Fenster)

The University of Rochester will house a new national center focused on using tissue-on-chip technology to develop drugs more rapidly and reduce the need for animal trials. The National Institutes of Health awarded a $7.5 million grant to establish the Translational Center for Barrier Microphysiological Systems (TraCe-bMPS) at Rochester in partnership with Duke University.

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