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Mapping Flow, Tapping Holes: Can We Do These With Ultrasound?

Alfred Yu, NSERC Steacie Fellow and Professor in Biomedical Engineering at the University of Waterloo, Canada

Wegmans Hall 1400

Ultrasound imaging is undoubtedly popular in today’s clinical practice. However, the current technology is known to have systemic limitations. Can we intuitively track complex flow with ultrasound? Can we consistently generate membrane pores with ultrasound? This seminar will introduce our laboratory's quest to devise high-frame-rate (>1000 fps) ultrasound flow imaging tools for vascular diagnostic applications and to apply advanced imaging tools for visualizing important wave-cell interactions in therapeutic ultrasound. Our ultrasound imaging innovations have enabled us to reveal complex vascular phenomena that arise in response to physiological stressors. Our cellular imaging investigations have unravelled various biophysical interactions between low-intensity ultrasound and living cells. A series of single-cell imaging findings will be presented, including the case where microbubbles are introduced as agents to induce acoustic cavitation.

Alfred Yu is an NSERC Steacie Fellow and Professor in Biomedical Engineering at the University of Waterloo, Canada. He leads the NSERC Collaborative Research Training Program on "Next-Generation Innovations in Ultrasonics" in Canada. Alfred has a long-standing research interest in ultrasound imaging and therapeutics. He is a Fellow of AIUM and EIC. He has been a recipient of the ISTU Frederic Lizzi Award, the IEEE Ultrasonics Early Career Investigator Award, the Ontario Early Researcher Award, and various best paper prizes at conferences. He is now the Editor-in-Chief of the IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, the Program Chair of 2023 IEEE Ultrasonics Symposium, and a Community Leader of the AIUM Basic Science and Instrumentation Group. He is also the Past Chair of ISTU Education Committee and the Medical Ultrasound Group of IEEE Ultrasonics Symposium.

Refreshments will be provided.